CLINICAL CONSIDERATIONS : Disorders of the limbic system

•  Emotional lability and various forms of psychosis can accompany hippocampal (and other limbic structures) disorders.

  Eating disorders : Many disorders from anorexia nervosa to bulimia may involve limbic system pathology.

•  Kluver-Bucy syndrome This comprises profound behavior changes in following bilateral removal of the temporal lobe (which houses neocortical areas, parahippocampal gyrus, uncus, and amygdala; and the hippocampal formation). The changes in behavior included:

  1. An increase in both amount and diversity of sexual activity . The hyper-sexuality includes heterosexual, homosexual and auto-sexual behaviors.
  2. Increase in oral activity .
  3. Increased docility and loss of fear.

•  Memory defects